RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-370
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-luciferase reporter assay
Target
TGF-betaRIII
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
The role of miR-370 in fibrosis after myocardial infarction
Year
2017
Function
"miR-370 also partially blocked TGF-beta1-TGF-betaRii and induced the downstream signal transduction pathways, thus exerting anti-fibrotic effects."